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  Product Description Kumar and Clark's Clinical Medicine is a comprehensive and authoritative single-volume   textbook   of internal medicine that is consulted by students and doctors throughout the world. Its aim is to explain the management of disease, based on an understanding of scientific   principles   and including the latest developments in treatment. It is written for medical students and doctors preparing for specialist exams, and is an ideal general reference text for all practising doctors. The new edition is part of Elsevier's new STUDENT CONSULT electronic community. STUDENT CONSULT titles comes with full text online, a unique image library, case studies, questions and answers, online note-taking, and integration links to content in other disciplines - ideal for problem-based learning. * Colour-coded chapters are attractive and make the book easy to navigate * Comprehensive index, clearly displayed, pinpoints information rapidly * Boxes and ta...

Outline with multiple-choice questions and answers for medical students and includes board-type questions with explanations at the end of the book. Scanned in black and white. # Paperback: 326 pages # Publisher: Lippincott Williams & Wilkins; Second Edition edition (August 15, 1998) # Language: English # ISBN-10: 0683303961 # ISBN-13: 978-0683303964 click here  

Homeostasis - maintains body's internal environment within a set of normal parameters Intrinsic regulation - cell/tissue/organ adjusts itself to environmental change Extrinsic regulation - nervous or endocrine systems adjust cell/tissue/organ to environmental change and coordinate other systems, requires long distance communication Nervous system - rapid, short-term, specific effect, limited targets; gap or synaptic Endocrine system - slower, long-term, broad effect, more targets; chemical messengers Exocrine glands - glandular cells secrete products into ducts Endocrine glands - glandular cells secrete products into ECF around gland Neuroendocrine - secreted by neuron endings into ECF Hormones Chemical messengers produced by endocrine glands which are usually carried in the circulatory system ...

When blood vessels are cut or damaged, the loss of blood from the system must be stopped before shock and possible death occur. This is accomplished by solidification of the blood, a process called coagulation or clotting. A blood clot consists of a plug of platelets enmeshed in a network of insoluble fibrin molecules. Platelet aggregation and fibrin formation both require the proteolytic enzyme thrombin . Clotting also requires: calcium ions (Ca 2+ )(which is why blood banks use a chelating agent to bind the calcium in donated blood so the blood will not clot in the bag). about a dozen other protein clotting factors . Most of these circulate in the blood as inactive precursors. They are activated by proteolytic cleavage becoming, in turn, active proteases for other factors in the system. By tradition, these factors are designated by Roman numerals. I find this somewhat confusing and will use Arabic numerals instead. Initiating the Clotting Process Damaged cells display a...

Hormones are the chemical messengers of the body. They are defined as organic substances secreted into blood stream to control the metabolic and biological activities. These hormones are involved in transmission of information from one tissue to another and from cell to cell. These substances are produced in small amounts by various endocrine (ductless) glands in the body. They are delivered directly to the blood in minute quantities and are carried by the blood to various target organs where these exert physiological effect and control metabolic activities. Thus frequently their site of action is away from their origin. Hormonesare required in trace amounts and are highly specific in their functions. The deficiency of any hormones leads to a particular disease, which can be cured by administration of that hormone. Classification of Hormones Hormones are classified on the basis of (i) their structure (ii) their site of activity in the cell. Steroids on which the above classification is...

KEY VOCABULARY   The following terms will be used during this lesson: ·          Conscious  - patient is awake and responds to stimuli appropriately ·          Coma  - patient is not aroused by external stimuli ·          Diabetes mellitus  - endocrine disorder characterized by inadequate insulin production by beta   cells in the islets of Langerhans in the pancreas ·          Endocrine Glands  - glands that secrete hormones directly into the blood stream ·          Glucose  – source of energy required by cells for normal functioning ·          Hyperglycemia  - abnormally high levels of glucose in the blood ·          Hypoglycemia  - abnormally low levels of gl...